3,974 research outputs found

    Evaluating the Effectiveness of the New Jersey Leaders to Leaders Induction Program: a Case Study

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    The effect of internal gravity waves on cloud evolution in sub-stellar atmospheres

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    Context. Sub-stellar objects exhibit photometric variability which is believed to be caused by a number of processes such as magnetically-driven spots or inhomogeneous cloud coverage. Recent sub-stellar models have shown that turbulent flows and waves, including internal gravity waves, may play an important role in cloud evolution.Aims. The aim of this paper is to investigate the effect of internal gravity waves on dust cloud nucleation and dust growth, and whether observations of the resulting cloud structures could be used to recover atmospheric density information.Methods. For a simplified atmosphere in two dimensions, we numerically solve the governing fluid equations to simulate the effect on dust nucleation and mantle growth as a result of the passage of an internal gravity wave. Furthermore, we derive an expression that relates the properties of the wave-induced cloud structures to observable parameters in order to deduce the atmospheric density.Results. Numerical simulations show that the density, pressure and temperature variations caused by gravity waves lead to an increase of dust nucleation by up to a factor 20, and dust mantle growth rate by up to a factor 1:6, compared to their equilibrium values. Through an exploration of the wider sub-stellar parameter space, we show that in absolute terms, the increase in dust nucleation due to internal gravity waves is stronger in cooler (T dwarfs) and TiO2-rich sub-stellar atmospheres. The relative increase however is greater in warm(L dwarf) and TiO2-poor atmospheres due to conditions less suited for efficient nucleation at equilibrium. These variations lead to banded areas in which dust formation is much more pronounced, and lead to banded cloud structures similar to those observed on Earth. Conclusions. Using the proposed method, potential observations of banded clouds could be used to estimate the atmospheric density of sub-stellar objects

    Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo

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    Neutrophil recruitment from blood to extravascular sites of sterile or infectious tissue damage is a hallmark of early innate immune responses, and the molecular events leading to cell exit from the bloodstream have been well defined1,2. Once outside the vessel, individual neutrophils often show extremely coordinated chemotaxis and cluster formation reminiscent of the swarming behaviour of insects3,4,5,6,7,8,9,10,11. The molecular players that direct this response at the single-cell and population levels within the complexity of an inflamed tissue are unknown. Using two-photon intravital microscopy in mouse models of sterile injury and infection, we show a critical role for intercellular signal relay among neutrophils mediated by the lipid leukotriene B4, which acutely amplifies local cell death signals to enhance the radius of highly directed interstitial neutrophil recruitment. Integrin receptors are dispensable for long-distance migration12, but have a previously unappreciated role in maintaining dense cellular clusters when congregating neutrophils rearrange the collagenous fibre network of the dermis to form a collagen-free zone at the wound centre. In this newly formed environment, integrins, in concert with neutrophil-derived leukotriene B4 and other chemoattractants, promote local neutrophil interaction while forming a tight wound seal. This wound seal has borders that cease to grow in kinetic concert with late recruitment of monocytes and macrophages at the edge of the displaced collagen fibres. Together, these data provide an initial molecular map of the factors that contribute to neutrophil swarming in the extravascular space of a damaged tissue. They reveal how local events are propagated over large-range distances, and how auto-signalling produces coordinated, self-organized neutrophil-swarming behaviour that isolates the wound or infectious site from surrounding viable tissue

    ENHANCING COASTAL DISASTER MITIGATION MEASURES: VEGETATION BASED FEASIBILITY STUDY FOR SOUTHERN JAVA, INDONESIA

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    Indonesia is a country that is prone to disaster especially earthquake and volcanic eruption because its located in the ring of fire. The type of disasters can produce another type of disaster which is: tsunami.  The nature of tsunamis that were hard to predict and arrive with little warning, Indonesians can minimize the effect of tsunami by creating coastal protection. In this study we look for the location to create the coastal forest as an enhancement of the mitigation effort. We conducted our study in the Pangandaran district as were a severe tsunami in the 2006 that caused more than 400 deaths. We conducted a suitability analysis to identify tsunami prone area based on the following criteria: should be had elevation <10m, slope gradient <2%, within proximity of 500m from coastline, and <100m from river and should be settlement or urban area. The creation of vulnerability map was using map algebra to calculate the weighted parameter from each class. Based our analysis using GIS analysis, the most vulnerable area in the Pangandaran district is the bay area, where we founded 1,419 acres of coastal area for which coastal forests could be planted to enhance protection against tsunamis.Â

    Compositional data analysis with Red-R

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    The compositional analyst must use a series of software to transform raw compositional data and run statistical analyses on them. Tools for compositional data analysis are available in R, an open source widely-used statistical computing environment. However, using R requires prior programming knowledge. Red-R is an open-source, user-friendly visual data flow interface based on R. The interface uses principles of pipeline programming where functions are represented as icons, termed widgets, and data flows from one function to another by drawing lines between them on a canvas. Red-R is able to perform common data analysis tasks (hypothesis tests, analysis of variance, regressions, principal component analysis, data cloud plots, bar plots, biplots, etc.). We have developed a novel Red-R package which implements the compositions package in R. Our compositions package can be used to perform compositional data operations over raw data (closure, additive, centered and isometric log ratio transformations, perturbations and powering, etc.), and create compositional plots (ternary diagrams, ilrdendrograms, etc.) without prior programming knowledge, after few basic operations. The objective of this work is to present Red-R and its compositions package using an application example for geochemical data. The network of widgets provides an easy-tofollow step-by-step procedure to run a large number of operations available in R, hence facilitating the tasks of the compositional data analyst. Furthermore, the entire analysis network can be saved and reloaded. Reports can be generated from the widget network to document and share results. Non-programmers can have an easy access to the advanced tools available in compositions analysis

    Optical microscopy via spectral modifications of a nano-antenna

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    The existing optical microscopes form an image by collecting photons emitted from an object. Here we report on the experimental realization of microscopy without the need for direct optical communication with the sample. To achieve this, we have scanned a single gold nanoparticle acting as a nano-antenna in the near field of a sample and have studied the modification of its intrinsic radiative properties by monitoring its plasmon spectrum.Comment: 6 pages, 4 figures (color

    MAPPING BUILDING INTERIORS WITH LIDAR: CLASSIFYING THE POINT CLOUD WITH ARCGIS

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    Accurate maps of building interiors are needed to support location-based services, plan for emergencies, and manage facilities. However, suitable maps to meet these needs are not available for many buildings. Handheld LiDAR scanners provide an effective tool to collect data for indoor mapping but there are no well-established methods for classifying features in indoor point clouds. The goal of this research was to develop an efficient manual procedure for classifying indoor point clouds to represent features-of-interest. We used Paracosm’s PX-80 handheld LiDAR scanner to collect point cloud and image data for 11 buildings, which encompassed a variety of architectures. ESRI’s ArcGIS Desktop was used to digitize features that were easily identified in the point cloud and Paracosm’s Retrace was used to digitize features for which imagery was needed for efficient identification. We developed several tools in Python to facilitate the process. We focused on classifying 29 features-of-interest to public safety personnel including walls, doors, windows, fire alarms, smoke detectors, and sprinklers. The method we developed was efficient, accurate, and allowed successful mapping of features as small as a sprinkler head. Point cloud classification for a 14,000 m2 building took 20–40 hours, depending on building characteristics. Although the method is based on manual digitization, it provides a practical solution for indoor mapping using LiDAR. The methods can be applied in mapping a wide variety of features in indoor or outdoor environments
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